Welcome to Gunma Univ. Graduate school of Medicine Integrative Physiology Nori. Koibuchi Lab.

講義・セミナー

講義

no information

セミナー

大学院セミナー

New insights into the epigenetic and metabolic actions of thyroid hormone

Paul M. Yen

Laboratory of Hormonal Regulation, Cardiovascular and
Metabolic Disease Program, Duke-NUS Graduate Medical School, Singapore

甲状腺ホルモンによるオートファジーとβ酸化促進を介する脂肪肝抑制機構についての新知見を中心に発表していただきます。

日時:平成23年11月28日(月)17:00-

場所:臨床大学院講堂

参考文献

Voss TC, Schiltz RL, Sung MH, Yen PM, et al. Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism. Cell. 2011; 146: 544-554.

Wang D, Xia X, Weiss RE, Refetoff S, Yen PM. Distinct and histone-specific modifications mediate positive versus negative transcriptional regulation of TSHα promoter. PLoS One 2010; 5:e9853

Wang D, Xia X, Liu Y, Oetting A, Cole PA, Meltzer P, Shi YB, Yen PM. Negative regulation of a target gene by thyroid hormone involves histone acetylation and corepressor complex dissociation. Mol Endocrinol 2009; 23:600-609.

Hu J, Xia X, Cheng A, Wang G, Luo X, Reed MF, Fojo, T. Oetting A, Gong J, Yen PM. A peptide inhibitor targeting p55PIK PI3K regulatory subunit: a novel cancer therapy. Molecular Cancer Therapeutics 2008; 7:3719-3728.

Liu Y, Xia X, Fondell JD, Yen PM. Thyroid hormone regulated genes have distinct patterns of co-activator recruitment and histone acetylation. Mol Endocrinol 2006; 20:483-490.

Maruvada P, NI Dmitrieva, J East-Palmer, Yen PM. Differential expression of thyroid hormone receptor during the cell cycle determines sensitivity to thyroid hormone. Mol Biol Cell 2004; 15:1895-1903.

応用生理学大学院講義を兼ねています。必要な方は出席してください。

powered by Quick Homepage Maker 4.91
based on PukiWiki 1.4.7 License is GPL. QHM

最新の更新 RSS  Valid XHTML 1.0 Transitional