Welcome to Gunma Univ. Graduate school of Medicine Integrative Physiology Nori. Koibuchi Lab.

業績集

過去3年間 2009年以降のみ掲載しております

原 著 Original reports

英文

原著

1. Takeshita A, Igarashi-Migitaka J, Nishiyama K, Takahashi H, Takeuchi Y, Koibuchi N. Acetyl tributyl citrate, the most widely used phthalate substitute plasticizer, induces cytochrome P450 3A through steroid and xenobiotic receptor. Toxicol Sci (in press).

2. Takahashi Y, Shimokawa N, Esmaeili-Mahani S, Morita A, Masuda H, Tamura J, Haglund K, Koibuchi N. 2011 Ligand-induced downregulation of TrkA is partly regulated through ubiquitination by Cbl. FEBS Lett 585: 1741-1747.

3. Ibhazehiebo K, Iwasaki T, Okano-Uchida T, Shimokawa N, Ishizaki Y, Koibuchi N. 2011 Suppression of thyroid hormone receptor-mediated transcription and disruption of thyroid hormone-induced cerebellar morphogenesis by the polybrominated biphenyl mixture, BP-6. Neurotoxicology 32: 400-409.

4. Ibhazehiebo K, Iwasaki T, Shimokawa N, Koibuchi N. 2011. Brain-derived neurotrophic factor (BDNF) ameliorates the suppression of thyroid hormone-induced granule cell neurite extension by hexabromocyclododecane (HBCD). Neurosci Lett 493: 1-7.

5. Takatsuru Y, Koibuchi N, Nabekura J. 2011 Unilateral infarction of the visual cortex (VC) induced an increase in dendritic spine turnover in contrallateral VC. Neurosci Lett 488: 97-100.

6. Sajdel-Sulkowska EM, Xu M, McGinnis W, Koibuchi N. 2011 Brain region-specific changes in oxidative stress and neurotrophin levels in autism spectrum disorders (ASD). Cerebellum 10: 43-48.

7. Ibhazehiebo K, Iwasaki T, Shimokawa N, Koibuchi N. 2011. 1,2,5,6,9,10-α Hexabromocyclododecane (HBCD) impairs thyroid hormone-induced dendrite arborization of Purkinje cells and suppresses thyroid hormone receptor-mediated transcription. Cerebellum10: 22-31.

8. Ibhazehiebo K, Iwasaki T, Kimura-Kuroda J, Miyazaki W, Shimokawa N, Koibuchi N. 2011. Disruption of thyroid hormone receptor-mediated transcription and thyroid hormone-induced Purkinje cell dendrite arborization by polybrominated diphenyl ethers. Env Health Perspect 119: 168-175.

9. Shimokawa N, Haglund K, Hölter SM, Grabbe C, Kirkin V, Koibuchi N, Schulz C, Rozman J, Hoeller D, Qiu CH, Londoño MB, Ikezawa J, Jedlicka P, Stein B, Schwarzacher SW, Wolfer DP, Ehrhardt N, Heuchel R, Nezis I, Brech A, Schmidt MH, Fuchs H, Gailus-Durner V, Klingenspor M, Bogler O, Wurst W, Deller T, de Angelis MH, Dikic I. 2010. CIN85 regulates dopamine receptor endocytosis and governs behavior in mice. EMBO J 29: 2421-2432.

10. Londoño M, Shimokawa N, Miyazaki W, Iwasaki T, Koibuchi N. 2010. Hydroxylated PCB induces Ca2+ oscillations and alteration of membrane potential in cultured cortical cells. J Appl Toxicol 30: 334-342.

11. Amano I, Miyazaki W, Iwasaki T, Shimokawa N, Koibuchi N. 2010. The effect of hydroxylated polychlorinated biphenyl (OH-PCB) on thyroid hormone receptor (TR)- mediated transcription through native-thyroid hormone response element (TRE). Industrial Health 48: 115-118.

12. Sajdel-Sulkowska EM, Xu, M, Koibuchi N. 2009. Cerebellar brain-derived neurotrophic factor, nerve growth factor, and neurotrophin-3 expression in male and female rats is differentially affected by hypergravity exposure during discrete developmental periods. Cerebellum 8: 454-462.

13. Sajdel-Sulkowska EM, Xu M, Koibuchi N. 2009. Increase in cerebellar neurotrophin-3 and oxidative stress markers in autism. Cerebellum 8: 366-372.

14. Qiu CH, Miyazaki W, Iwasaki T, Londoño M, Ibhazehiebo K, Shimokawa N, Koibuchi N. 2009. Retinoic acid receptor-related orphan receptor alpha-enhanced thyroid hormone receptor-mediated transcription requires its ligand binding domain which is not, by itself, sufficient: possible direct interaction of two receptors. Thyroid19: 893-898.

15. Odawara H, Iwasaki T, Horiguchi J, Rokutanda N, Hirooka K, Miyazaki W, Koibuchi Y, Shimokawa N, Iino Y, Takeyoishi I, Koibuchi N. 2009. Activation of aromatase expression by retinoic acid receptor-related orphan receptor (ROR)α in breast cancer cells: Identification of a novel ROR response element. J Biol Chem 284: 17711-17719.

総説

1 Koibuchi N. 2011. Cytochrome P450 (CYP) 1A1; is it involved in disruption of thyroid hormone action by polychlorinated biphenyl (PCB)? Exp Rev Endocrinol Metab (in press)

2. Koibuchi N. 2010. Mechanism of chemical disruptors of thyroid function. Hot Thyroidology HT 12/10 (epub).

3. Koibuchi N. 2009. Animal models to study thyroid hormone action in cerebellum Cerebellum 8: 89-97.

4. Koibuchi N. 2008. The role of thyroid hormone on cerebellar development. Cerebellum 7: 530-533.

5. Koibuchi N, Kimura-Kuroda J, Ikeda Y, Tsutsui K. 2008. Cerebellum, a target for hormonal signaling. Cerebellum 7: 499-504.

6. Koibuchi N. 2008. Hormonal regulation of cerebellar development and plasticity. Cerebellum 7: 1-3

7. Koibuchi N, Iwasaki T. 2006. Regulation of brain development by thyroid hormone and its modulation by environmental chemicals. Endocrine J. 53: 295-303.

8. Shimokawa N, Londono M, Koibuchi N. 2006. Gene expression and signaling pathways by extracellular acidification. Adv Exp Med Biol 580: 267-274.

著書

1. Koibuchi N. 2006. Thyroid hormone action in developing brain and its modulation by polyhalogenated aromatic hydrocarbons. In: C. Kubo, T. Kuboki (eds). Psychosomatic Medicine, International Congress Series Vol. 1287, Elsevier, Amsterdam pp 190-194.

2. Miyazaki W, Londono MB, Iwasaki T, Shimokawa N, Koibuchi N. 2008. Possible mechanisms of PCB action, which are not mediated by AhR. In: M. Morita (ed). Persistent Organic Pollutants (POPs) Research in Asia pp289-291

3. Sajdel-Sulkowska EM, Koibuchi N. Sexually-dimorphic nature of PCB effects on the developing animal CNS. In: Kestler L, Lewis M (eds) American Psychological Association, APS Books, Washington (in press)

4. Manto, M.; Gruol, D.; Schmahmann, J.; Koibuchi, N.; Rossi, F. (Eds.) Handbook of the Cerebellum and Cerebellar Disorders
Springer Reference

和文

著書

1. 鯉淵典之 甲状腺 2011 In:ギャノング生理学 原書23版 (Kim E. 他 著  岡田 泰伸 監訳)丸善出版
ギャノング生理学

2. 鯉淵典之 ホルモンの構造からみた分類と作用機序他 2011 In: 内分泌・栄養・代謝系 コア・カリキュラムテキスト(寺内,鯉淵,後藤 編) 文光堂
s内分泌・代謝必修エッセンス.jpg

3. 鯉淵典之(分担執筆)2010 生物学辞典 東京科学同人
生物学辞典

4. 鯉淵典之(監訳) 2010インテグレーテッドシリーズ5 生理学 東京科学同人
インテグレーテッドシリーズ5 生理学

5. 岩崎俊晴,鯉淵典之 現代人を取り巻く疾病 2010 In: 生物の事典(石原勝敏、末光隆志編) 朝倉書店 pp.346-357.
現代人を取り巻く疾病

6. 鯉淵典之 2009 胎児と新生児の生理 (訳) In: オックスフォード生理学 (植村慶一 ed.) 丸善 pp535-551.
オックスフォード生理学

7. 鯉淵典之 2009 身体に必要な栄養素 (訳) In: オックスフォード生理学 第3版 (植村慶一 ed.)  丸善 pp.469-481.

8. 鯉淵典之 監訳 2009 症例問題から学ぶ生理学「原書3版」 丸善
症例問題から学ぶ生理学

9. 鯉淵典之 内分泌系(訳)2009 In: みえる人体 構造・機能・病態(佐藤達夫,松尾理 監訳) 南江堂 pp102-111.
みえる人体 構造・機能・病態

10. 鯉淵典之 カルシウム代謝の内分泌制御 2009 In: 標準生理学 第7版 (小沢瀞司,福田康一郎編)医学書院 pp. 966-974.
標準生理学

11. 鯉淵典之 下川哲昭 乳房/内分泌・栄養・代謝系(鯉淵) 生殖機能(下川) 2008 In: カラーイラストで学ぶ集中講義 生理学(岡田隆夫 編)MEDICAL VIEW pp.276-319.
カラーイラストで学ぶ集中講義 生理学

12. 鯉淵典之(分担執筆)2007 看護師国家試験 解剖生理学クリアブック 2007 日本生理学会教育委員会編 医学書院
解剖生理学クリアブック

原著,総説

1. 岩崎俊晴,鯉淵典之 2011甲状腺ホルモン受容体に及ぼす内分泌かく乱物質の新たな作用 (in press)

2. 鯉淵典之 2011甲状腺ホルモン作用のかく乱による環境化学物質の発達神経毒性動物心理学研究 (in press)

3. 鯉淵典之,小山徹也 2011 甲状腺の解剖と病理 Modern Physician 31 (4): 377-381.

4. 鯉淵典之 2010 「教育のページ」日本生理学会教育委員会活動内容の紹介とこれからの活動方針 日本生理学雑誌  72: 228-230.

5. 鯉淵典之 2010 論文紹介:変異によりAllan-Herndon-Dudley症候群を生じる神経細胞型T3輸送体Mct8遺伝子を欠損したマウスニューロンにおける3’,3,5-トリヨードサイロニン(T3)取り込みと行動表現型の解析 日本甲状腺学会雑誌1(2): 138.

6. 小田原宏樹,岩崎俊晴,堀口淳,鯉淵幸生,六反田奈和,時庭英彰,飯野佑一,竹吉泉,鯉淵典之 2010 核内ホルモン受容体RORαによるアロマターゼ遺伝子の新たな活性化機序 乳癌基礎研究 19:19-23.

特 許 Patent

岩崎俊晴,鯉淵典之
Toshiharu Iwasakki, Noriyuki Koibuchi

タンパク質 – 標的物質の結合検出法
Liquid Chemiluminescent DNA Pull down Assay

特許 第 4631058 号
特願 2006-064876

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